Maternal vaginal fluids play a major role in the colonization of the neonatal intestinal microbiota.

ABSTRACT:

Background

Caesarean section (CS) is associated with newborns' health risks due to the blocking of microbiome transfer. The gut microbiota of CS-born babies was different from those born vaginally, which may be attributed to reduced exposure to maternal vaginal microbes during labour. To understand the microbial transfer and reduce CS disadvantages, the effect of vaginal microbiota exposure on infant gut microbiota composition was evaluated using 16s rDNA sequencing-based techniques.

Results

Pregnant women were recruited in the Women and Children's Hospital, School of Medicine, Xiamen University from June 1^st to August 15^th, 2017. Maternal faeces (n = 26), maternal vaginal fluids (n = 26), and neonatal transitional stools (n = 26) were collected, while

SUBMITTER: Xie J 

PROVIDER: S-EPMC10061231 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature