Association of Glucose-6-Phosphate Dehydrogenase Deficiency With Outcomes in US Veterans With COVID-19.

ABSTRACT:

Importance

The underlying biological risk factors for severe outcome due to SAR-CoV-2 infection are not well defined.

Objective

To determine the association between glucose-6-phosphate dehydrogenase (G6PD) deficiency and severity of COVID-19.

Design, setting, and participants

This retrospective cohort study included analysis of 24 700 veterans with G6PD enzyme testing prior to January 1, 2020, obtained through the US Veterans Health Administration national databases. These veterans were cross-referenced with the Veterans Administration COVID-19 Shared Data Resource for SARS-CoV-2 testing from February 15, 2020, to January 1, 2021. The final study population consisted of 4811 veterans who tested positive for SARS-CoV-2. Statistical analysis was performed from June to D

SUBMITTER: Elsea SH 

PROVIDER: S-EPMC10061239 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature