Oncologic outcomes in breast cancer patients with metastatic nodes and pathological nodal response following neoadjuvant chemotherapy without axillary dissection: a literature review.

ABSTRACT:

Background and objective

With promising nodal pathological complete response (pCR) after neoadjuvant chemotherapy, the role of axillary lymph node dissection (ALND) was questioned. While there is much data on the accuracy of axillary staging after neoadjuvant chemotherapy to predict nodal pCR, limited data on the oncological safety of omitting ALND exists. We aim to review the oncological safety of omitting ALND in patients with initially metastatic nodes achieving nodal pCR, based on axillary staging, following neoadjuvant chemotherapy.

Methods

A PubMed search of relevant articles from 1^st January 2013 to 15^th September 2022 was performed. Studies with duplication of patients, ALND only, no oncological details, initially N0 patients only and patients w

SUBMITTER: Lim GH 

PROVIDER: S-EPMC10061475 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature