Relevance of Microvascular Flow Assessments in Critically Ill Neonates and Children: A Systematic Review.

ABSTRACT:

Objectives

Resolution of impaired microvascular flow may lag the normalization of macrocirculatory variables. The significance of microcirculatory dysfunction in critically ill children and neonates is unknown, but microcirculatory variables can be measured using Doppler or videomicroscopy imaging techniques. We outline the current understanding of the role of the microcirculation in critical illness, review methods for its assessment, and perform a systematic review of how it has been monitored in critically ill neonates and children.

Design

Systematic review (PROSPERO CRD42019117993).

Setting

Not applicable.

Subjects

Not applicable.

Interventions

None.

Measurements and results

We systematically searched MEDLINE, EMBASE, PubMed, and Web of Scienc

SUBMITTER: Maitoza LA 

PROVIDER: S-EPMC10061570 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature