Relationship between fibrinogen level and advanced colorectal adenoma among inpatients: A retrospective case-control study.

ABSTRACT:

Objective

This study was to explore the relationship between fibrinogen and advanced colorectal adenoma among inpatients.

Methods

From April 2015 to June 2022, 3738 participants (566 case subjects and 3172 control subjects) who underwent colonoscopies enrolled, and smooth curve fitting and logistic regression models were applied to explore the association between fibrinogen and advanced colorectal adenoma. In addition, sensitivity and subgroup analyses were performed to assess the stability of the results.

Results

Compared with lower fibrinogen quantile 1 (< 2.4 g/L), the adjusted OR values for fibrinogen and advanced colorectal adenoma in quantile 2 (2.4-2.75 g/L), quantile 3 (2.76-3.15 g/L), and quantile 4 (≥3.16 g/L) were 1.03 (95% confidence interval [CI]: 0.76-1.

SUBMITTER: Wang H 

PROVIDER: S-EPMC10061582 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature