Development of Pipetteless Paper-Based Analytical Devices with a Volume Gauge.

ABSTRACT: In this work, we propose a new design for paper-based analytical devices (PADs) that eliminate the need to use a micropipette for sample introduction. With this design, a PAD is equipped with a distance-based detection channel that is connected to a storage channel that indicates the volume of a sample introduced into the PAD. The analyte in the sample solution reacts with a colorimetric reagent deposited into the distance-based detection channel as the sample solution flows into the storage channel where the volume is measured. The ratio of the lengths of the detection channel and that of the storage channel (D/S ratio) are constant for a sample containing a certain concentration, which is independent of the introduced volume. Therefore, the PADs permit volume-independent qu

SUBMITTER: Danchana K 

PROVIDER: S-EPMC10061644 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature