Impact of previous malignancy at diagnosis on oncological outcomes of upper tract urothelial carcinoma.

ABSTRACT:

Background

The evidence of prognostic factors and individualized surveillance strategies for upper tract urothelial carcinoma are still weak.

Objectives

To evaluate whether the history of previous malignancy (HPM) affects the oncological outcomes of upper tract urothelial carcinoma (UTUC).

Methods

The CROES-UTUC registry is an international, observational, multicenter cohort study on patients diagnosed with UTUC. Patient and disease characteristics from 2380 patients with UTUC were collected. The primary outcome of this study was recurrence-free survival. Kaplan-Meier and multivariate Cox regression analyses were performed by stratifying patients according to their HPM.

Results

A total of 996 patients were included in this study. With a median recurrence-free s

SUBMITTER: Zhao H 

PROVIDER: S-EPMC10061966 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature