Development of a nomogram based on serum cytokine-related riskscore in breast cancer.

ABSTRACT:

Background

Cytokines are involved in many inflammatory diseases and thus play an important role in tumor immune regulation. In recent years, researchers have found that breast cancer is not only related to genetic and environmental factors, but also to the chronic inflammation and immunity. However, the correlation between serum cytokines and blood tests indicators remain unclear.

Methods

A total of 84 serum samples and clinicopathological data of breast cancer patients from Tianjin Cancer Institute & Hospital, Tianjin Medical University, Tianjin, P. R. China were collected. The expression levels of the 12 cytokines were detected by immunofluorescence method. Blood tests results were obtained from medical records. By stepwise Cox regression analysis, a cytokine-related gene

SUBMITTER: Zhu Y 

PROVIDER: S-EPMC10062183 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature