Evaluation of multi-channel phase reconstruction methods for quantitative susceptibility mapping on postmortem human brain.

ABSTRACT: Quantitative Susceptibility Mapping (QSM) is an established Magnetic Resonance Imaging (MRI) technique with high potential in brain iron studies associated to several neurodegenerative diseases. Unlike other MRI techniques, QSM relies on phase images to estimate tissue's relative susceptibility, therefore requiring a reliable phase data. Phase images from a multi-channel acquisition should be reconstructed in a proper way. On this work it was compared the performance of combination of phase matching algorithms (MCPC3D-S and VRC) and phase combination methods based on a complex weighted sum of phases, considering the magnitude at different powers (k = 0 to 4) as the weighting factor. These reconstruction methods were applied in two datasets: a simulated brain dataset for a 4-coil arr

SUBMITTER: Otsuka FS 

PROVIDER: S-EPMC10062192 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature