Unmet needs and perspectives in rheumatoid arthritis-associated interstitial lung disease: A critical review.

ABSTRACT: Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease characterized by synovitis as the most common clinical manifestation, and interstitial lung disease (RA-ILD) represents one of the most common and potentially severe extra-articular features. Our current understanding of the mechanisms and predictors of RA-ILD is limited despite the demonstration that an early identification of progressive fibrosing forms is crucial to provide timely treatment with antifibrotic therapies. While high resolution computed tomography is the gold standard technique for the diagnosis and follow-up of RA-ILD, it has been hypothesized that serum biomarkers (including novel and rare autoantibodies), new imaging techniques such as ultrasound of the lung, or the application of innovative radiologic al

SUBMITTER: Stainer A 

PROVIDER: S-EPMC10062456 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature