The representation of females in clinical trials for substance use disorder conducted in the United States (2010-19).

ABSTRACT:

Background and aims

Women have historically been under-represented in clinical research, but the extent to which this is true for substance use disorder (SUD) trials is unknown. We aimed to determine the ratio of female:male participation in clinical trials for SUDs and describe the reporting of sex-specific outcomes from 2010 to 2019.

Design

A retrospective cohort review of clinical trials involving people with SUD.

Setting

United States.

Participants

Clinical trials including people with SUD registered in clinicaltrials.gov and completed between 1 January 2010 and 31 December 2019 were reviewed. Trials were excluded if they had < 30 participants, focused on SUD prevention, were conducted outside the United States and/or did not report data on participant sex

SUBMITTER: Gunn CM 

PROVIDER: S-EPMC10062729 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature