Association of multi-metals with the risk of hypertension and the interaction with obesity: A cross-sectional study in China.

ABSTRACT:

Background

Environmental exposure to multiple metals have been inconsistently associated with hypertension. Obesity is an important independent risk factor for hypertension, and few studies have assessed the interaction between obesity and metals in this context. We aimed to clarify their association and interaction.

Methods

This cross-sectional study included 3,063 adults from 11 districts or counties, Guangdong. We measured the whole blood levels of 13 metals and used multipollutant-based statistical methods to analyze the association of metals with hypertension. The interaction between metals and obesity on hypertension was assessed on additive and multiplicative scales.

Results

Four metals (manganese, arsenic, cadmium, and lead) were significantly associated with

SUBMITTER: Wu S 

PROVIDER: S-EPMC10063192 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature