Case report: Immune remission from generalized myasthenia gravis in a dog with a thymoma and cholangiocellular carcinoma.

ABSTRACT: A 9-year-old male neutered Cockapoo was presented with an acute and progressive history of exercise induced weakness involving all limbs, and bilateral decreased ability to blink. Investigations revealed generalized myasthenia gravis alongside the presence of a thymoma and a cholangiocellular carcinoma. Symptomatic treatment through pyridostigmine bromide was used to control clinical signs, and complete surgical removal of the thymoma and cholangiocellular carcinoma was performed. Serum acetylcholine receptor antibody concentration was measured serially. Clinical remission defined as resolution of clinical signs alongside discontinuation of treatment was achieved by day 251 (8.2 months). Immune remission defined as normalization of serum acetylcholine receptor antibody concentration alongs

SUBMITTER: Mignan T 

PROVIDER: S-EPMC10063851 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature