ABC transporters linked to multiple herbicide resistance in blackgrass (Alopecurus myosuroides).

ABSTRACT: Enhanced detoxification is a prominent mechanism protecting plants from toxic xenobiotics and endows resistance to diverse herbicide chemistries in grass weeds such as blackgrass (Alopecurus myosuroides). The roles of enzyme families which impart enhanced metabolic resistance (EMR) to herbicides through hydroxylation (phase 1 metabolism) and/or conjugation with glutathione or sugars (phase 2) have been well established. However, the functional importance of herbicide metabolite compartmentalisation into the vacuole as promoted by active transport (phase 3), has received little attention as an EMR mechanism. ATP-binding cassette (ABC) transporters are known to be important in drug detoxification in fungi and mammals. In this study, we identified three distinct C-class ABCCs transport

SUBMITTER: Goldberg-Cavalleri A 

PROVIDER: S-EPMC10063862 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature