Antibodies to SARS-CoV-2 in follicular fluids and their association with assisted reproduction.

ABSTRACT:

Introduction

Every second woman suffering from infertility asks for medical help. There is public concern that vaccination-induced antibodies (Ab) are negatively associated with fertility. A recent study has demonstrated an association between SARS-CoV-2 vaccination and a lower pregnancy rate in the subsequent 60 days. Consequently, Ab could affect fertility success in assisted reproduction.

Methods

To address this question, we compared fertilization outcomes of vaccinated (n=35) and nonvaccinated (n=34) women. Paired serum samples and multiple follicular fluids (FF) (up to 10 from the same donor) were collected during the course of assisted reproduction and characterized for oocyte quality, the presence of Ab and trace element concentrations.

Results

The results show

SUBMITTER: Chillon TS 

PROVIDER: S-EPMC10064043 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature