Richer than we thought: neurophysiological methods reveal rich-club network development is frequency- and sex-dependent.

ABSTRACT: A set of highly connected brain regions called the "rich-club" are vital in integrating information across the functional connectome. Although the literature has identified some changes in rich-club organization with age, little is known about potential sex-specific developmental trajectories, and neurophysiologically relevant frequency-dependent changes have not been established. Here we examine the frequency- and sex-dependent development of rich-club organization using magnetoencephalography in a large normative sample (N = 383) over a wide age span (4-39 years). We report strong divergence between males and females across alpha, beta, and gamma frequencies. While males show increased or no change in rich-club organization with age, females show a consistent, non-linear trajector

SUBMITTER: Vandewouw MM 

PROVIDER: S-EPMC10064222 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature