Racial Disparities in Pathological Complete Response Among Patients Receiving Neoadjuvant Chemotherapy for Early-Stage Breast Cancer.

ABSTRACT:

Importance

Among patients with breast cancer, inconsistent findings have been published on racial disparities in achieving pathologic complete response (pCR) after neoadjuvant chemotherapy (NACT).

Objective

To investigate whether racial disparities exist in achieving pCR and what factors contribute to them.

Design, setting, and participants

Within the ongoing Chicago Multiethnic Epidemiologic Breast Cancer Cohort (ChiMEC), which consists of a prospectively ascertained cohort of patients with breast cancer, 690 patients with stage I to III breast cancer receiving NACT were identified for this single-institution study at the University of Chicago Medicine. Patients diagnosed between 2002 and 2020 (median follow-up: 5.4 years) were included; next-generation sequencing da

SUBMITTER: Zhao F 

PROVIDER: S-EPMC10064259 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature