Systematic review and meta-analysis of the efficacy of benzodiazepines for dyspnea in patients with cancer.

ABSTRACT:

Objective

the role of benzodiazepines in relieving dyspnea in patients with cancer has not yet been established. This systematic review and meta-analysis aimed to determine the efficacy and safety of benzodiazepines alone or in combination with opioids for dyspnea in patients with cancer.

Methods

Cochrane Central Register of Controlled Trials, MEDLINE, EMBASE and Ichushi-Web were searched for articles published from database inception to 23 September 2019. Studies of benzodiazepines alone or in combination with opioids for dyspnea were included. The primary outcome measure was the relief of dyspnea. The secondary outcome measures were anxiety, somnolence and severe adverse events.

Results

of 505 publications initially identified, two trials and one trial were included

SUBMITTER: Yasuda S 

PROVIDER: S-EPMC10064324 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature