Comparison of IVIg and TPE efficacy in the treatment of neurological disorders: a systematic literature review

ABSTRACT:

Background:

Intravenous immunoglobulin (IVIg) and therapeutic plasma exchange (TPE) are among the main immunotherapies for neurological disorders. Their benefit is greatest in immune-mediated conditions, but their distinct efficacy cannot be simply explained.

Objectives:

This review aimed to systematically identify studies comparing the efficacy of TPE and IVIg treatments for selected autoimmune neurological disorders and identify optimal therapies for each condition.

Data Sources and Methods:

PubMed, MEDLINE and Embase databases were searched for original publications from 1990 to 2021. Additional publications were identified via expert recommendations. Conference abstracts older than 2017, review articles and articles without information on TPE and IVIg compari

SUBMITTER:  

PROVIDER: S-EPMC10064470 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature