Behavioral context affects social signal representations within single primate prefrontal cortex neurons.

ABSTRACT: We tested whether social signal processing in more traditional, head-restrained contexts is representative of the putative natural analog-social communication-by comparing responses to vocalizations within individual neurons in marmoset prefrontal cortex (PFC) across a series of behavioral contexts ranging from traditional to naturalistic. Although vocalization-responsive neurons were evident in all contexts, cross-context consistency was notably limited. A response to these social signals when subjects were head-restrained was not predictive of a comparable neural response to the identical vocalizations during natural communication. This pattern was evident both within individual neurons and at a population level, as PFC activity could be reliably decoded for the behavioral context in whi

SUBMITTER: Jovanovic V 

PROVIDER: S-EPMC10064486 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature