Acute kidney injury in patients with idiopathic membranous nephropathy: influencing factors and prognosis.

ABSTRACT:

Aim

Idiopathic membranous nephropathy (IMN) is a common type of nephrotic syndrome, and is associated with acute kidney injury (AKI). We investigated the association of multiple variables with AKI in patients with IMN.

Methods

The data of 187 patients with biopsy-proven IMN were examined. Renal outcome was defined as progression to end-stage renal disease (ESRD). Binary logistic regression and Kaplan-Meier's analysis were used for statistical analysis.

Results

During follow-up, 46 (24.6%) patients developed AKI. The incidence of AKI was greater in males than females (p < .01). The AKI group had higher uric acid, lower serum PLA2R antibody positive, and worse baseline kidney function (all p < .01). Most patients in the AKI group had stage I (71.74%) or st

SUBMITTER: Li Z 

PROVIDER: S-EPMC10064812 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature