Case report: Multiple disconnection patterns revealed by a multi-modal analysis explained behavior after a focal frontal damage.

ABSTRACT:

Introduction

There is overwhelming evidence that focal lesions cause structural, metabolic, functional, and electrical disconnection of regions directly and indirectly connected with the site of injury. Unfortunately, methods to study disconnection (positron emission tomography, structural and functional magnetic resonance imaging, electroencephalography) have been applied primarily in isolation without capturing their interaction. Moreover, multi-modal imaging studies applied to focal lesions are rare.

Case report

We analyzed with a multi-modal approach the case of a patient presenting with borderline cognitive deficits across multiple domains and recurrent delirium. A post-surgical focal frontal lesion was evident based on the brain anatomical MRI. However, we were able to

SUBMITTER: Monai E 

PROVIDER: S-EPMC10064861 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature