Gait and falls in cerebral small vessel disease: a systematic review and meta-analysis.

ABSTRACT:

Background

Gait impairment contributes to falls and frailty. Some studies suggest that cerebral small vessel disease (CSVD) is associated with gait impairment in the general population. We systematically reviewed and meta-analysed the literature on associations of CSVD with gait impairment and falls.

Methods

The protocol was published in PROSPERO (CRD42021246009). Searches of Medline, Cochrane and Embase databases were conducted on 30 March 2022. Cross-sectional and longitudinal studies of community-dwelling adults were included, reporting relationships between diagnosis or neuroimaging markers of CSVD and outcomes related to gait or falls. Partial correlation coefficients were calculated and pooled using a random-effects model for meta-analysis.

Results

The search re

SUBMITTER: Sharma B 

PROVIDER: S-EPMC10064981 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature