Impact of PCV10 on pediatric pneumococcal disease burden in Brazil: time for new recommendations?

ABSTRACT:

Objective

To describe the impact of the 10-valent pneumococcal conjugate vaccine on the pediatric burden of pneumococcal infections, carriage, serotype replacement, and antimicrobial resistance in Brazil since its introduction in 2010.

Data source

A narrative review of English, Spanish, and Portuguese articles published in online databases and in Brazilian epidemiological surveillance databases was performed. The following keywords were used: Streptococcus pneumoniae, pneumococcal disease, conjugate vaccine, PCV10, antimicrobial resistance, and meningitis.

Summary of the findings

Declines in hospitalization rates of all-cause pneumonia occurred in the target age groups and some age groups not targeted by vaccination early after the use of PCV10. Large descriptive stud

SUBMITTER: Jarovsky D 

PROVIDER: S-EPMC10066423 | biostudies-literature | 2023 Mar-Apr

REPOSITORIES: biostudies-literature