Population Study of Sex-Based Outcomes After Surgical Aortic Valve Replacement.

ABSTRACT:

Background

Surgical aortic valve replacement (SAVR) is a key strategy for the treatment of aortic valve disease. However, studies have involved primarily male patients, and whether the benefits of this approach can be extrapolated to female patients is unclear.

Methods

Clinical and administrative datasets for 12,207 patients undergoing isolated SAVR in Ontario from 2008 to 2019 were linked. Male and female patients were balanced using inverse probability treatment weighting. Mortality, endocarditis, and major hemorrhagic and thrombotic events, as well as 2 composite outcomes-major adverse cerebral and cardiovascular events (MACCE) and patient-derived adverse cardiovascular and noncardiovascular events (PACE)-and their component events, were compared in the weighted groups wi

SUBMITTER: Rubens FD 

PROVIDER: S-EPMC10066438 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature