Sex variation in colorectal cancer mortality: trends and implications for screening.

ABSTRACT:

Background

Colorectal cancer (CRC) screening using faecal tests reduces disease-specific mortality. To investigate mortality and its association with sex, rates in women and men, and in different age ranges, were examined, before and after screening began in Scotland.

Methods

From 1990-99, no structured screening existed. Three pilots ran from 2000 to 2007 and subsequent full roll-out completed in 2009. Crude mortality rates for 1990-2020 were calculated relative to Scottish population estimates, and age-sex standardized rates calculated for all, pre-screening (<50 years), screening (5-74 years) and post-screening (>74 years) age ranges.

Results

CRC mortality declined from 1990 to 2020, but not linearly, and differed between sexes. In women, 1990-99 showed a steady de

SUBMITTER: Clark GRC 

PROVIDER: S-EPMC10066495 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature