Phylodynamic analysis of HIV-1 subtypes B, C and CRF 02_AG in Senegal.

ABSTRACT: Surveillance of HIV epidemics in key populations and in developing countries is often challenging due to sparse, incomplete, or low-quality data. Analysis of HIV sequence data can provide an alternative source of information about epidemic history, population structure, and transmission patterns. To understand HIV-1 dynamics and transmission patterns in Senegal, we carried out model-based phylodynamic analyses using the structured-coalescent approach using HIV-1 sequence data from three different subgroups: reproductive aged males and females from the adult Senegalese population and men who have sex with other men (MSM). We fitted these phylodynamic analyses to time-scaled phylogenetic trees individually for subtypes C and CRF 02_AG, and for the combined data for subtypes B, C and CRF 02_A

SUBMITTER: Nascimento FF 

PROVIDER: S-EPMC10066795 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature