Clinical outcomes of non-nasopharyngeal lymphoepithelial carcinoma treated with a combined modality approach: A single-institution study.

ABSTRACT:

Background

This study presents a summary of the clinical characteristics of non-nasopharyngeal lymphoepithelial carcinoma (NNPLEC), effects of combined modality treatment and prognostic value of plasma Epstein-Barr virus (EBV) deoxyribonucleic acid (DNA) load, with the aim of providing a reference framework for optimizing treatment practices and outcomes.

Methods

Patients with NNPLEC treated by our center between January 2000 and December 2020 were retrospectively reviewed.

Results

In total, 728 patients were included. The lung was identified as the most common primary tumor site (64.0%), followed by the salivary gland (19.2%). A total of 539 (74.0%) patients underwent surgery, 459 (63.0%) received chemotherapy, and 361 (49.6%) were subjected to radiotherapy. The medi

SUBMITTER: Qiu Z 

PROVIDER: S-EPMC10067105 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature