Tellu - an object-detector algorithm for automatic classification of intestinal organoids.
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ABSTRACT:
SUBMITTER: Domenech-Moreno E
PROVIDER: S-EPMC10067441 | biostudies-literature | 2023 Mar
REPOSITORIES: biostudies-literature
Publications
Tellu - an object-detector algorithm for automatic classification of intestinal organoids.
Domènech-Moreno Eva E Brandt Anders A Lemmetyinen Toni T TT Wartiovaara Linnea L Mäkelä Tomi P TP Ollila Saara S
Disease models & mechanisms 20230313 3
Intestinal epithelial organoids recapitulate many of the in vivo features of the intestinal epithelium, thus representing excellent research models. Morphology of the organoids based on light-microscopy images is used as a proxy to assess the biological state of the intestinal epithelium. Currently, organoid classification is manual and, therefore, subjective and time consuming, hampering large-scale quantitative analyses. Here, we describe Tellu, an object-detector algorithm trained to classify ...[more]
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