The prognostic value of the combination of body composition and systemic inflammation in patients with cancer cachexia.

ABSTRACT:

Background

Changes in body composition and systemic inflammation are important characteristics of cancer cachexia. This multi-centre retrospective study aimed to explore the prognostic value of the combination of body composition and systemic inflammation in patients with cancer cachexia.

Methods

The modified advanced lung cancer inflammation index (mALI), which combines body composition and systemic inflammation, was defined as appendicular skeletal muscle index (ASMI) × serum albumin/neutrophil-lymphocyte ratio. The ASMI was estimated according to a previously validated anthropometric equation. Restricted cubic splines were used to evaluate the relationship between mALI and all-cause mortality in patients with cancer cachexia. Kaplan-Meier analysis and Cox proportional haz

SUBMITTER: Xie HL 

PROVIDER: S-EPMC10067477 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature