Defining reference values for body composition indices by magnetic resonance imaging in UK Biobank.

ABSTRACT:

Background

Magnetic resonance imaging (MRI) is the gold standard for evaluating body composition. However, the reference ranges have not been established.

Methods

Three lean tissue and seven adipose tissue parameters based on MRI data from the UK Biobank were used in this study. Participants with European ancestry and data on at least one parameter were screened. Age- and sex-specific percentile curves were generated using the lambda-mu-sigma method. Three levels of reference ranges were provided, which were equivalent to the mean ± 1 standard deviation (SD), 2 SDs and 2.5 SDs.

Results

The final analysis set for each parameter ranged from 4842 to 14 148 participants (53.4%-56.6% women) with a median age of 61. For lean tissue parameters, compared with those at age 45,

SUBMITTER: Dai L 

PROVIDER: S-EPMC10067500 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature