Associations between multimorbidity and frailty transitions among older Americans.

ABSTRACT:

Background

The associations of multimorbidity patterns with transitions between frailty states remain unclear in older individuals.

Methods

We used data from the National Health and Aging Trends Study 2011-2019. Frailty was measured annually using the Fried frailty phenotype. Multimorbidity patterns at baseline were identified using latent class analysis based on 14 chronic conditions. We used the semi-Markov multi-state model to investigate the influences of multimorbidity characterized by condition counts and patterns on subsequent frailty transitions over follow-ups.

Results

Among 9450 participants aged ≥65 years at baseline, 34.8% were non-frail, 48.1% were pre-frail and 17.0% were frail. Over a median follow-up of 4.0 years, 16 880 frailty transitions were observ

SUBMITTER: Luo Y 

PROVIDER: S-EPMC10067509 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature