Association of preterm outcome with maternal systemic lupus erythematosus: a retrospective cohort study.

ABSTRACT:

Background

Maternal systemic lupus erythematosus (SLE) is at greater risk of pregnancy complications and is associated with increased risk of preterm delivery. However hardly any study has looked at the influence of SLE on the outcomes of preterm infants. This study aimed to explore the influence of SLE on the outcomes of preterm infants.

Methods

In this retrospective cohort study, preterm infants born to mothers with SLE from Shanghai Children's Medical Center during 2012 to 2021 were enrolled. Infants were excluded if they were died during hospitalization or has major congenital anomalies and neonatal lupus. Exposure was defined as mother diagnosed SLE before or during pregnancy. Maternal SLE group was matched with Non-SLE group by gestational age, birth weight and gender.

SUBMITTER: Chen X 

PROVIDER: S-EPMC10068147 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature