Differences in clinical characteristics and quantitative lung CT features between vaccinated and not vaccinated hospitalized COVID-19 patients in Italy.

ABSTRACT:

Background

To evaluate the differences in the clinical characteristics and severity of lung impairment, assessed by quantitative lung CT scan, between vaccinated and non-vaccinated hospitalized patients with COVID-19; and to identify the variables with best prognostic prediction according to SARS-CoV-2 vaccination status. We recorded clinical, laboratory and quantitative lung CT scan data in 684 consecutive patients [580 (84.8%) vaccinated, and 104 (15.2%) non-vaccinated], admitted between January and December 2021.

Results

Vaccinated patients were significantly older 78 [69-84] vs 67 [53-79] years and with more comorbidities. Vaccinated and non-vaccinated patients had similar PaO₂/FiO₂ (300 [252-342] vs 307 [247-357] mmHg; respiratory rate 22 [8-26] vs

SUBMITTER: Chiumello D 

PROVIDER: S-EPMC10068232 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature