Health outcomes of penicillin allergy testing in children: a systematic review.

ABSTRACT:

Background

Penicillin allergy labels are commonly acquired in childhood and lead to avoidance of first-line penicillin antibiotics. Understanding the health outcomes of penicillin allergy testing (PAT) can strengthen its place in antimicrobial stewardship efforts.

Objectives

To identify and summarize the health outcomes of PAT in children.

Methods

Embase, MEDLINE, Web of Science, Cochrane Library, SCOPUS and CINAHL were searched from inception to 11 Oct 2021 (Embase and MEDLINE updated April 2022). Studies that utilized in vivo PAT in children (≤18 years old) and reported outcomes relevant to the study objectives were included.

Results

Thirty-seven studies were included in the review, with a total of 8411 participants. The most commonly reported outcomes were d

SUBMITTER: Kwok M 

PROVIDER: S-EPMC10068421 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature