Obesity, Body Composition, and Sex Hormones: Implications for Cardiovascular Risk.

ABSTRACT: Cardiovascular disease (CVD) continues to be the leading cause of death in adults, highlighting the need to develop novel strategies to mitigate cardiovascular risk. The advancing obesity epidemic is now threatening the gains in CVD risk reduction brought about by contemporary pharmaceutical and surgical interventions. There are sex differences in the development and outcomes of CVD; premenopausal women have significantly lower CVD risk than men of the same age, but women lose this advantage as they transition to menopause, an observation suggesting potential role of sex hormones in determining CVD risk. Clear differences in obesity and regional fat distribution among men and women also exist. While men have relatively high fat in the abdominal area, women tend to distribute a larger propo

SUBMITTER: Singh P 

PROVIDER: S-EPMC10068688 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature