Kb_DRAM: annotation and metabolic profiling of genomes with DRAM in KBase.

ABSTRACT: Microbial genome annotation is the process of identifying structural and functional elements in DNA sequences and subsequently attaching biological information to those elements. DRAM is a tool developed to annotate bacterial, archaeal, and viral genomes derived from pure cultures or metagenomes. DRAM goes beyond traditional annotation tools by distilling multiple gene annotations to genome level summaries of functional potential. Despite these benefits, a downside of DRAM is the requirement of large computational resources, which limits its accessibility. Further, it did not integrate with downstream metabolic modeling tools that require genome annotation. To alleviate these constraints, DRAM and the viral counterpart, DRAM-v, are now available and integrated with the freely accessible KB

SUBMITTER: Shaffer M 

PROVIDER: S-EPMC10068739 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature