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Type of syncope and outcome in Brugada syndrome: A systematic review and meta-analysis.


ABSTRACT:

Introduction

Brugada syndrome is an inherited arrhythmic disease associated with major arrhythmic events (MAE). The importance of primary prevention of sudden cardiac death (SCD) in Brugada syndrome is well recognized; however, ventricular arrhythmia risk stratification remains challenging and controversial. We aimed to assess the association of type of syncope with MAE via systematic review and meta-analysis.

Methods

We comprehensively searched the databases of MEDLINE and EMBASE from inception to December 2021. Included studies were cohort (prospective or retrospective) studies that reported the types of syncope (cardiac, unexplained, vasovagal, and undifferentiated) and MAE. Data from each study were combined using the random-effects, generic inverse variance method of De

SUBMITTER: Rattanawong P 

PROVIDER: S-EPMC10068940 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature