Transmission of oral microbiota to the biliary tract during endoscopic retrograde cholangiography.

ABSTRACT:

Background

Endoscopic retrograde cholangiography (ERC) possesses a translocation risk of microbes to the biliary system. We studied bile contamination during ERC and its impact on patients' outcome in a real-life-situation.

Methods

Ninety-nine ERCs were analyzed and microbial samples were taken from the throat before and from bile during ERC and from irrigation fluid of the duodenoscope before and after ERC.

Results

91.2% of cholangitis patients had detectable microbes in the bile (sensitivity 91%), but the same was true for 86.2% in the non-cholangitis group. Bacteroides fragilis (p=0.015) was significantly associated with cholangitis. In 41.7% of ERCs with contaminated endoscopes these microbes were found in the bile after the procedure. Analysis of duodenoscopes' i

SUBMITTER: Effenberger M 

PROVIDER: S-EPMC10069052 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature