Cardiometabolic risk indicators in individuals with bipolar disorders: a replication study.

ABSTRACT:

Objectives

We recently conducted the first longitudinal study comparing cardiometabolic risk indicators (CMRIs) between a cohort of individuals with bipolar disorders (BDs) and controls from the general population. Here, we sought to validate the findings in that study using an independent case-control sample.

Methods

We used data from the St. Göran project's Gothenburg cohort. The BDs group and the control group were examined at baseline and after a median of eight and seven years, respectively. Data collection occurred between March 2009 and June 2022. We used multiple imputation to handle missing data and linear mixed effects model to examine the annual change in CMRIs over the study period.

Results

The baseline cohort included 407 individuals with BDs (mean age 40

SUBMITTER: Najar H 

PROVIDER: S-EPMC10069119 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature