Regular medication as a risk factor for intracranial aneurysms: A comparative case-control study.

ABSTRACT:

Background

Previous medical history strongly contributes to the genesis of intracranial aneurysms (IA). A possible impact of regular medication on the occurrence of abdominal aortic aneurysms has been reported.

Aim

To evaluate the value of regular medication on the risk of development and rupture of IA.

Methods

Data on medication use and related comorbidities were obtained from the institutional IA registry. A 1:1 age- and sex-matched patient sample was collected from the population-based Heinz Nixdorf Recall Study with individuals from the same area.

Results

In the analysis comparing IA cohort (n = 1960) with the matched normal population (n = 1960), the use of statins (adjusted odds ratio, 1.34 [95% confidence interval 1.02-1.78]), antidiabetics

SUBMITTER: Jabbarli R 

PROVIDER: S-EPMC10069188 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature