Cardiac autonomic dysfunction and risk of incident stroke among adults with type 2 diabetes.

ABSTRACT:

Introduction

There is a dearth of data on the association between cardiac autonomic neuropathy (CAN) with incident stroke among individuals with diabetes mellitus. We evaluated this association in a large sample of adults with type 2 diabetes.

Patients and methods

Participants with type 2 diabetes from the Action to Control Cardiovascular Risk in Diabetes (ACCORD) study without atherosclerotic cardiovascular disease at baseline were included. CAN was assessed at baseline by heart rate variability (HRV) indices and QT index (QTI) calculated from 10-s resting electrocardiograms. HRV was assessed using standard deviation of all normal-to-normal R-Rs intervals (SDNN) and root mean square of successive differences between normal-to-normal R-R intervals (rMSSD). CAN was defined ba

SUBMITTER: Kaze AD 

PROVIDER: S-EPMC10069192 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature