Copper(i)-catalyzed click chemistry in deep eutectic solvent for the syntheses of β-d-glucopyranosyltriazoles.

ABSTRACT: In the last two decades, click chemistry has progressed as a powerful tool in joining two different molecular units to generate fascinating structures with a widespread application in various branch of sciences. copper(i)-catalyzed azide-alkyne cycloaddition (CuAAC) reaction, also known as click chemistry, has been extensively utilized as a versatile strategy for the rapid and selective formation of 1,4-disubstituted 1,2,3-triazoles. The successful use of CuAAC reaction for the preparation of biologically active triazole-attached carbohydrate-containing molecular architectures is an emerging area of glycoscience. In this regard, a well-defined copper(i)-iodide complex (1) with a tridentate NNO ligand (L₁) was synthesized and effectively utilized as an active catalyst. Instead of

SUBMITTER: Sethi S 

PROVIDER: S-EPMC10069229 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature