Agreement and reliability of hepatic transient elastography in patients with chronic hepatitis C: A cross-sectional test-retest study.

ABSTRACT:

Background and aims

Transient elastography (TE) has largely replaced liver biopsy to evaluate fibrosis stage and cirrhosis in chronic hepatitis C. Previous studies have reported excellent reliability of TE but agreement metrics have not been reported. This study aimed to assess interrater agreement and reliability of repeated TE measurements.

Methods

Two operators performed TE independently, directly after each other. The primary outcome was disagreement, defined as a difference in TE results between operators of ≥33%, as well as the smallest detectable change, SDC₉₅ (i.e., the difference between measurements needed to state with 95% certainty that there is a difference in underlying stiffness). Secondary outcomes included reliability, measured as intraclass corre

SUBMITTER: Ljungquist O 

PROVIDER: S-EPMC10069238 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature