High-flow nasal cannula reduces intubation rate in patients with COVID-19 with acute respiratory failure: a meta-analysis and systematic review.

ABSTRACT:

Objective

This study aimed to investigate the effect of high-flow nasal cannula therapy (HFNC) versus conventional oxygen therapy (COT) on intubation rate, 28-day intensive care unit (ICU) mortality, 28-day ventilator-free days (VFDs) and ICU length of stay (ICU LOS) in adult patients with acute respiratory failure (ARF) associated with COVID-19.

Design

Systematic review and meta-analysis.

Data sources

PubMed, Web of Science, Cochrane Library and Embase up to June 2022.

Eligibility criteria for selecting studies

Only randomised controlled trials or cohort studies comparing HFNC with COT in patients with COVID-19 were included up to June 2022. Studies conducted on children or pregnant women, and those not published in English were excluded.

Data extraction an

SUBMITTER: Li Y 

PROVIDER: S-EPMC10069279 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature