Tracking functional network connectivity dynamics in the elderly.

ABSTRACT:

Introduction

Functional magnetic resonance imaging (fMRI) has shown that aging disturbs healthy brain organization and functional connectivity. However, how this age-induced alteration impacts dynamic brain function interaction has not yet been fully investigated. Dynamic function network connectivity (DFNC) analysis can produce a brain representation based on the time-varying network connectivity changes, which can be further used to study the brain aging mechanism for people at different age stages.

Method

This presented investigation examined the dynamic functional connectivity representation and its relationship with brain age for people at an elderly stage as well as in early adulthood. Specifically, the resting-state fMRI data from the University of North Carolina coho

SUBMITTER: Wu K 

PROVIDER: S-EPMC10069653 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature