Mechanisms and functions of respiration-driven gamma oscillations in the primary olfactory cortex.

ABSTRACT: Gamma oscillations are believed to underlie cognitive processes by shaping the formation of transient neuronal partnerships on a millisecond scale. These oscillations are coupled to the phase of breathing cycles in several brain areas, possibly reflecting local computations driven by sensory inputs sampled at each breath. Here, we investigated the mechanisms and functions of gamma oscillations in the piriform (olfactory) cortex of awake mice to understand their dependence on breathing and how they relate to local spiking activity. Mechanistically, we find that respiration drives gamma oscillations in the piriform cortex, which correlate with local feedback inhibition and result from recurrent connections between local excitatory and inhibitory neuronal populations. Moreover, respiration-dr

SUBMITTER: Gonzalez J 

PROVIDER: S-EPMC10069865 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature