Positive schizotypy is associated with amplified mnemonic discrimination and attenuated generalization.

ABSTRACT: Tendency to experience inaccurate beliefs alongside perceptual anomalies constitutes positive schizotypal traits in the general population and shows continuity with the positive symptoms of schizophrenia. It has been hypothesized that the positive symptomatology of schizophrenia, and by extension, the odd beliefs and unusual perceptual experiences in the general population, are associated with specific alterations in memory functions. An imbalance between memory generalization and episodic memory specificity has been proposed on several counts; however, the direction of the imbalance is currently unclear. Here, we evaluated the association between positive schizotypy, and memory alterations related to hippocampal computations in a general population sample enriched for positive schizotypy.

SUBMITTER: Vass A 

PROVIDER: S-EPMC10070292 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature