Pharmacological management of acute spinal cord injury: a longitudinal multi-cohort observational study.

ABSTRACT: Multiple types and classes of medications are administered in the acute management of traumatic spinal cord injury. Prior clinical studies and evidence from animal models suggest that several of these medications could modify (i.e., enhance or impede) neurological recovery. We aimed to systematically determine the types of medications commonly administered, alone or in combination, in the transition from acute to subacute spinal cord injury. For that purpose, type, class, dosage, timing, and reason for administration were extracted from two large spinal cord injury datasets. Descriptive statistics were used to describe the medications administered within the first 60 days after spinal cord injury. Across 2040 individuals with spinal cord injury, 775 unique medications were administered wit

SUBMITTER: Jutzeler CR 

PROVIDER: S-EPMC10070428 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature