Sleep apnea-COPD overlap syndrome is associated with larger left carotid atherosclerotic plaques.

ABSTRACT:

Background

Little is known about whether the overlap syndrome (OS) combining features of chronic obstructive pulmonary disease (COPD) and sleep apnea-hypopnea syndrome increases the risk of stroke associated with COPD itself.

Methods

We prospectively studied 74 COPD patients and 32 subjects without lung disease. Spirometry and cardiorespiratory polygraphy were used to assess the pulmonary function of the study population and ultrasound measurements of intima media thickness (IMT) as well as the volume of plaques in both carotid arteries were also evaluated.

Results

Polygraphic criteria of OS were met in 51% of COPD patients. We found that 79% of patients with OS and 50% of COPD patients without OS had atherosclerotic plaques in the left carotid artery (p = 0.05

SUBMITTER: Landete P 

PROVIDER: S-EPMC10070750 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature